ZLN005-d4
Based on 1 Customer Validation
ZLN005-d4 is deuterium labeled ZLN005. ZLN005 is a potent activator of peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α).
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.52%
- CAS 番号: 2410443-42-2
- 分子式: C17H14D4N2
- 分子量:254.36
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
化学情報
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CAS 番号 2410443-42-2
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非標識Cas 49671-76-3
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性状 Solid
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分子量 254.36
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分子式 C17H14D4N2
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Color White to off-white
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SMILES
CC(C)(C1=CC=C(C=C1)C2=NC3=C([2H])C([2H])=C([2H])C([2H])=C3N2)C
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 22 mg/mL (86.49 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (271 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Zhang LN, et al. Novel small-molecule PGC-1α transcriptional regulator with beneficial effects on diabetic db/db mice. Diabetes. 2013 Apr;62(4):1297-307. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.9314 mL | 19.6572 mL | 39.3144 mL | 98.2859 mL |
| 5 mM | 0.7863 mL | 3.9314 mL | 7.8629 mL | 19.6572 mL | |
| 10 mM | 0.3931 mL | 1.9657 mL | 3.9314 mL | 9.8286 mL | |
| 15 mM | 0.2621 mL | 1.3105 mL | 2.6210 mL | 6.5524 mL | |
| 20 mM | 0.1966 mL | 0.9829 mL | 1.9657 mL | 4.9143 mL | |
| 25 mM | 0.1573 mL | 0.7863 mL | 1.5726 mL | 3.9314 mL | |
| 30 mM | 0.1310 mL | 0.6552 mL | 1.3105 mL | 3.2762 mL | |
| 40 mM | 0.0983 mL | 0.4914 mL | 0.9829 mL | 2.4571 mL | |
| 50 mM | 0.0786 mL | 0.3931 mL | 0.7863 mL | 1.9657 mL | |
| 60 mM | 0.0655 mL | 0.3276 mL | 0.6552 mL | 1.6381 mL | |
| 80 mM | 0.0491 mL | 0.2457 mL | 0.4914 mL | 1.2286 mL |
ZLN005-d4 関連分類
HY-17538S 関連分類
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