CDK7-IN-5
CDK7-IN-5 is a CDK7 inhibitor with an IC50 value <100 nM. CDK7-IN-5 has anticancer effects. (WO2015154022A1 (Compound 104)).
For research use only. We do not sell to patients.
- CAS No.: 1817006-50-0
- Formula: C34H45N9O2
- Molecular Weight:611.78
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
CDK7 <100 nM (IC50) |
In Vitro
CDK7-IN-5 (Comp 104; 72 hours) inhibits the proliferation of A673 cells with an IC50 <500 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 1817006-50-0
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Molecular Weight 611.78
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Formula C34H45N9O2
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SMILES
CC(C1=C2N(N=C1)C(NCC3=C(C=CC=C3)NCC4=CC=C(C=C4)NC(/C=C/CN(C)C)=O)=NC(OC5CCN(CC5)C)=N2)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CDK7-IN-5 Related Classifications
HY-139986 Related Classifications
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