Progesterone-d9
Based on 1 Customer Validation
Progesterone-d9 is the deuterium labeled Progesterone. Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.
For research use only. We do not sell to patients.
- Purity: 99.66%
- CAS No.: 15775-74-3
- Formula: C21H21D9O2
- Molecular Weight:323.52
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 15775-74-3
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Unlabeled Cas 57-83-0
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Appearance Solid
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Molecular Weight 323.52
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Formula C21H21D9O2
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Color White to light yellow
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SMILES
C[C@]12[C@]([H])([C@@]3(CC([2H])(C4=C(C(C([2H])(C[C@@]4([C@]3(CC2)[H])C)[2H])=O)[2H])[2H])[H])CC[C@@]1(C(C([2H])([2H])[2H])=O)[2H]
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Synonyms
Pregn-4-ene-3,20-dione-d9
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 25 mg/mL (77.27 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (277 KB)
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SDS (419 KB)
- English - EN (419 KB)
- Français - FR (419 KB)
- Deutsch - DE (419 KB)
- Norwegian - NO (419 KB)
- Español - ES (419 KB)
- Swedish - SV (419 KB)
- Italian - IT (419 KB)
- Korean - KR (419 KB)
- Portuguese - PT (419 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Schindler AE, et al. Classification and pharmacology of progestins. Maturitas. 2003 Dec 10;46 Suppl 1:S7-S16. [Content Brief]
[3]. Zava DT, et al. Estrogen and progestin bioactivity of foods, herbs, and spices. Proc Soc Exp Biol Med. 1998 Mar;217(3):369-78. [Content Brief]
[4]. Komesaroff PA, et al. Effects of wild yam extract on menopausal symptoms, lipids and sex hormones in healthy menopausal women. Climacteric. 2001 Jun;4(2):144-50. [Content Brief]
[5]. Girling JE, et al. Progesterone, but not estrogen, stimulates vessel maturation in the mouse endometrium. Endocrinology. 2007 Nov;148(11):5433-41. Epub 2007 Aug 9. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.0910 mL | 15.4550 mL | 30.9100 mL | 77.2750 mL |
| 5 mM | 0.6182 mL | 3.0910 mL | 6.1820 mL | 15.4550 mL | |
| 10 mM | 0.3091 mL | 1.5455 mL | 3.0910 mL | 7.7275 mL | |
| 15 mM | 0.2061 mL | 1.0303 mL | 2.0607 mL | 5.1517 mL | |
| 20 mM | 0.1545 mL | 0.7727 mL | 1.5455 mL | 3.8637 mL | |
| 25 mM | 0.1236 mL | 0.6182 mL | 1.2364 mL | 3.0910 mL | |
| 30 mM | 0.1030 mL | 0.5152 mL | 1.0303 mL | 2.5758 mL | |
| 40 mM | 0.0773 mL | 0.3864 mL | 0.7727 mL | 1.9319 mL | |
| 50 mM | 0.0618 mL | 0.3091 mL | 0.6182 mL | 1.5455 mL | |
| 60 mM | 0.0515 mL | 0.2576 mL | 0.5152 mL | 1.2879 mL |
Progesterone-d9 Related Classifications
HY-N0437S Related Classifications
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