1,2-Hexanediol
Based on 1 Customer Validation
1,2-Hexanediol (Hexane-1,2-diol) is a broad-spectrum antibacterial agent. 1,2-Hexanediol exhibits bactericidal activity against Gram-positive and Gram-negative bacteria, as well as antifungal activity against fungal organisms. 1,2-Hexanediol disrupts the cytoplasmic membrane potential of bacteria. 1,2-Hexanediol can be used in research on bacterial and fungal infections, as well as cosmetic preservation.
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- CAS No.: 6920-22-5
- 화학식: C6H14O2
- 분자량:118.18
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보관:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
1,2-hexanediol (195-100000 ppm; 24-72 h) inhibits the growth of Escherichia coli NCTC 12923, Staphylococcus aureus NCTC 10788, Candida albicans NCPF 3179, and Aspergillus brasiliensis NCPF 2275, with MIC values of 12500, 25000, 12500, and 6250 ppm, respectively[1].
1,2-hexanediol (0-25000 ppm; 24-48 h) exerts synergistic inhibitory effects with Nicotinamide (HY-B0150) against Candida albicans NCPF 3179 and Aspergillus brasiliensis NCPF 2275, with FICI values of 0.375 and 0.3125, respectively; it exerts synergistic inhibitory effects with sodium cocoyl methyl taurate and sodium cocoyl alaninate against Escherichia coli NCTC 12923, with an FICI value of 0.375 for each combination; it also exerts a synergistic inhibitory effect with sodium C14-16 olefin sulfonate against Aspergillus brasiliensis NCPF 2275, with an FICI value of 0.375[1].
1,2-Hexanediol disrupts the cytoplasmic membrane potential of B. cereus ATCC 21772[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 6920-22-5
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Appearance Liquid (Density: 0.951 g/cm3)
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분자량 118.18
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화학식 C6H14O2
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Color Colorless to light yellow
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SMILES
OCC(O)CCCC
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Synonyms
Hexane-1,2-diol
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
순도&문서
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Data Sheet (264 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Handling Instructions (2659 KB)
References
[1]. Gim H, et al. Synergistic/antagonistic antimicrobial effects of cosmetic ingredients in combination with 1,2-hexanediol. J Microorg Control. 2024;29(4):133-142. [Content Brief]
[2]. Yogiara, et al. Food-grade antimicrobials potentiate the antibacterial activity of 1,2-hexanediol. Lett Appl Microbiol. 2015;60(5):431-439. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
1,2-Hexanediol Related Classifications
HY-W012880 Related Classifications
Powered by Bioz
- 1,2-Hexanediol
- 6920-22-5
- Hexane-1,2-diol
- Environmental Pollutants
- Fungal
- Bacterial
- bacterial cytoplasmic membrane potential
- niacinamide
- Staphylococcus aureus NCTC 10788
- Aspergillus brasiliensis NCPF 2275
- fungi
- Escherichia coli NCTC 12923
- Gram-positive bacteria
- Gram-negative bacteria
- Candida albicans NCPF 3179
- Bacillus cereus
- ntimicrobial agent
- Inhibitor
- inhibitor
- inhibit