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Cat. No.: HY-124114

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4-Hydroxytoremifene

Name: 4-Hydroxytoremifene
Brand: MedChemExpress
SKU: HY-124114
Price: 440.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: 4-OH-TOR)

4-Hydroxytoremifene (4-OH-TOR) is an estrogen receptor antagonist that blocks the uterus's ability to absorb estradiol.

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CAS No.: 110503-62-3
화학식: C₂₆H₂₈ClNO₂
분자량:421.96

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

4-Hydroxytoremifene Chemical Structure

CAS No.: 110503-62-3

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

4-Hydroxytoremifene (4-OH-TOR) is an estrogen receptor antagonist that blocks the uterus's ability to absorb estradiol^[1].

All Estrogen Receptor/ERR Isoforms :

Chemical Information

CAS No. 110503-62-3
분자량 421.96
화학식 C₂₆H₂₈ClNO₂
SMILES

OC1=CC=C(C=C1)/C(C2=CC=C(C=C2)OCCN(C)C)=C(CCCl)/C3=CC=CC=C3
Synonyms

4-OH-TOR
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocol

All Signal Pathway Related

Research Protocol for Endocrine Diseases
Endocrine diseases often arise from disrupted hormone production, hormone signaling, or target-tissue responsiveness; for diabetes-focused endocrine disease models, insulin signaling regulates glucose uptake, hepatic glucose output, lipid metabolism, and β-cell compensation. Type 2 diabetes develops through interacting defects in insulin resistance, β-cell dysfunction, adipose inflammation, hepatic glucose overproduction, altered incretin signaling, and ectopic lipid metabolism. A major unresolved question is whether endocrine dysfunction is driven primarily by target-tissue insulin resistance, intrinsic β-cell failure, immune/inflammatory stress, or combined multi-organ failure that differs by disease stage.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. N H Simberg, et al. In vitro and in vivo binding of toremifene and its metabolites in rat uterus. J Steroid Biochem. 1990 Jun 22;36(3):197-202. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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