8-Bromoadenine
Based on 1 Customer Validation
8-Bromoadenine (8-Bromo-9H-purin-6-amine) is a DNA radiosensitizer that inhibits DNA single-strand break repair in cells. 8-Bromoadenine is a brominated derivative of adenine, and radioactive adenine can be prepared by replacing bromine with deuterium.
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- Purity: 98.92%
- CAS No.: 6974-78-3
- 화학식: C5H4BrN5
- 분자량:214.02
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보관:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
All DNA/RNA Synthesis Isoforms
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Biological Activity
8-Bromoadenine (0.1 mM; 30-90 min) inhibits DNA single-strand break repair in HeLa-M cell monolayer cultures. And after γ irradiation, the quality of DNA synthesized by cells is lower than that of DNA synthesized by cells without purine addition[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 6974-78-3
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Appearance Solid
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분자량 214.02
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화학식 C5H4BrN5
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Color Off-white to yellow
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SMILES
BrC1=NC2=C(N1)C(N)=NC=N2
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Synonyms
8-Bromo-9H-purin-6-amine
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선적
Room temperature in continental US; may vary elsewhere.
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보관
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
용액&용해도
0.1 M NaOH : 0.2 mg/mL (0.93 mM; ultrasonic and warming and heat to 60°C)
순도&문서
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Data Sheet (270 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)