K-Ras G12C-IN-2
K-Ras G12C-IN-2 is an irreversible covalent K-Ras G12C inhibitor.
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- CAS No.: 1629267-75-9
- 화학식: C21H27ClN4O3
- 분자량:418.92
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보관:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
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Biological Activity
제품 설명
IC50 & Target
[1]|
KRas G12C |
In Vitro
Chemical Information
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CAS No. 1629267-75-9
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Appearance Solid
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분자량 418.92
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화학식 C21H27ClN4O3
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Color White to off-white
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SMILES
ClC1=C(C2CC2)C=C(NCC(N3CCN(C4CN(C(C=C)=O)C4)CC3)=O)C(O)=C1
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
In Vitro:
DMSO : ≥ 22 mg/mL (52.52 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (268 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3871 mL | 11.9355 mL | 23.8709 mL | 59.6773 mL |
| 5 mM | 0.4774 mL | 2.3871 mL | 4.7742 mL | 11.9355 mL | |
| 10 mM | 0.2387 mL | 1.1935 mL | 2.3871 mL | 5.9677 mL | |
| 15 mM | 0.1591 mL | 0.7957 mL | 1.5914 mL | 3.9785 mL | |
| 20 mM | 0.1194 mL | 0.5968 mL | 1.1935 mL | 2.9839 mL | |
| 25 mM | 0.0955 mL | 0.4774 mL | 0.9548 mL | 2.3871 mL | |
| 30 mM | 0.0796 mL | 0.3978 mL | 0.7957 mL | 1.9892 mL | |
| 40 mM | 0.0597 mL | 0.2984 mL | 0.5968 mL | 1.4919 mL | |
| 50 mM | 0.0477 mL | 0.2387 mL | 0.4774 mL | 1.1935 mL |
K-Ras G12C-IN-2 Related Classifications
HY-18605 Related Classifications
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