Albicanol
Albicanol is a sesquiterpenoid with potent antioxidant and antagonistic activities against heavy metal toxicity. Albicanol shows cytotoxicity. Albicanol suppress Profenofos (HY-B0832) induced genotoxicity in grass carp hepatocytes.
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- CAS No.: 54632-04-1
- 화학식: C15H26O
- 분자량:222.37
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
Albicanol (compound 6) (0-30 µM; 48 h) shows cytotoxicity with IC50s of >30, 24.14, >30 µM for A549, MCF7, HepG2 cells, respectively[1].
Albicanol (0.00005 µg/mL; 24 h) significantly inhibits the genotoxicity of L8824 cells resulted from PFF exposure[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:A549, MCF7, HepG2 cells
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Concentration:0-30 µM
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Incubation Time:48 h
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Result:Showed cytotoxicity with IC50s of >30, 24.14, >30 µM for A549, MCF7, HepG2 cells, respectively.
Chemical Information
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CAS No. 54632-04-1
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분자량 222.37
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화학식 C15H26O
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SMILES
CC(C)(CCC[C@@]1([C@H]2CO)C)[C@@H]1CCC2=C
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Structure Classification
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Initial Source
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Zhao DD, et al. Compounds from Dryopteris fragrans (L.) Schott with cytotoxic activity. Molecules. 2014 Mar 18;19(3):3345-55. [Content Brief]
[2]. Lihui X, et al. Albicanol modulates oxidative stress and the p53 axis to suppress profenofos induced genotoxicity in grass carp hepatocytes. Fish Shellfish Immunol. 2022 Mar;122:325-333. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Albicanol Related Classifications
HY-119635 Related Classifications
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