Aureothin
Aureothin, is a natural polyketide, is a HIV inhibitor with an IC50 of 5.3 nM. Aureothin is a microbial biolarvicide.
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- CAS No.: 2825-00-5
- 화학식: C22H23NO6
- 분자량:397.42
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
제품 설명
IC50 & Target
[2]|
HIV 5.3 nM (IC50) |
In Vitro
Aureothin shows larvicidal activity against A. aegypti with a LC50 value of 1.5 ppm for 24 h post-treatment, and 3.8 ppm for 48 h post-treatment[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2825-00-5
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분자량 397.42
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화학식 C22H23NO6
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SMILES
CC1=C([C@H]2C/C(CO2)=C/C(C)=C/C3=CC=C(C=C3)[N+]([O-])=O)OC(OC)=C(C1=O)C
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Initial Source
Streptomyces thioluteus
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
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Data Sheet (269 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Seong Jong Kim, et al. Streptomyces distallicus, a Potential Microbial Biolarvicide. J Agric Food Chem. 2022 Sep 14;70(36):11274-11280. [Content Brief]
[2]. Alexander Herrmann, et al. Potent inhibition of HIV replication in primary human cells by novel synthetic polyketides inspired by Aureothin. Sci Rep. 2020 Jan 28;10(1):1326. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)