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Cat. No.: HY-112738

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AX048

Name: AX048
Brand: MedChemExpress
SKU: HY-112738
Price: 623.00 USD
Availability: InStock
Rating: 5 (1 reviews)

AX048 is an inhibitor for calcium-dependent phospholipase A2 cPLA₂ with a X_I(50) of 0.022 mole fraction and reveals an antihyperalgesic efficacy.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 873079-69-7
화학식: C₂₂H₄₁NO₄
분자량:383.57

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (262 KB)

AX048 Chemical Structure

CAS No.: 873079-69-7

사이즈

가격

재고

수량

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vivo
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

AX048 is an inhibitor for calcium-dependent phospholipase A2 cPLA₂ with a X_I(50) of 0.022 mole fraction and reveals an antihyperalgesic efficacy^[1].

IC₅₀ & Target

cPLA₂

All Phospholipase Isoforms :

In Vivo

AX048 (0-30 mg/kg, i.p.) reduces the thermal hyperalgesia with the ED₅₀ of 1.2 mg/kg in Sprague Dawle rats^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

Carrageenan-induced thermal hyperalgesia in Sprague Dawley rats^[1]
Dosage:

0-30 mg/kg
Administration:

i.p.
Result:

Reduced the escape latencies in a dose-dependent manner.

Chemical Information

CAS No. 873079-69-7
분자량 383.57
화학식 C₂₂H₄₁NO₄
SMILES

O=C(C(CCCCCCCCCCCCCC)=O)NCCCC(OCC)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (262 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Yaksh TL, et al., Systemic and intrathecal effects of a novel series of phospholipase A2 inhibitors on hyperalgesia and spinal prostaglandin E2 release. J Pharmacol Exp Ther. 2006 Jan;316(1):466-75. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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Other size

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vivo
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

상품명:
CAS No.:
Species:
Purity:
수량:

AX048

All Phospholipase Isoforms

Biological Activity

제품 설명

IC50 & Target

In Vivo

Chemical Information

순도&문서

References

Calculators

Help & FAQs

AX048 Related Classifications

HY-112738 Related Classifications

Bioz

Keywords

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