Copy Link Print Information

BAY-3827

18 Cited Publications
고객리뷰

Based on 18 publication(s) in Google Scholar

BAY-3827, a chemical probe, is a potent and selective AMPK inhibitor with IC50 values of 1.4 nM at low (10 μM ATP concentration) and 15 nM at high (2 mM ATP concentration). BAY-3827 shows over 500-fold selectivity for most of the 331 kinases. BAY-3827 prevents phosphorylation of acetyl-CoA carboxylase 1 and shows strongest anti-proliferative activity in androgen-dependent prostate cancer cell lines.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

  • Purity: 99.72%
  • CAS No.: 2377576-35-5
  • 화학식: C27H25FN6O
  • 분자량:468.53
  • 보관:

    4°C, protect from light

    * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

  • BAY-3827 Chemical Structure
    BAY-3827 Chemical Structure
  • Experimental Validation Results for BAY-3827
  • Experimental Validation Results for BAY-3827
  • Experimental Validation Results for BAY-3827
  • Experimental Validation Results for BAY-3827
  • Experimental Validation Results for BAY-3827
CAS No.: 2377576-35-5
사이즈
가격
재고
수량
Amount: USD 0.00
Please select quantity
or
or

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Data Download

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
주변의 대리점 찾기 Your local distributor: Hycultec GmbHHycultec
  • Biological Activity
  • Chemical Information
  • 용액&용해도
  • 순도&문서
  • References
  • Help & FAQs
You May Still Need
Top Publications Citing

Use of MCE Products

Publications Citing Use of MedChemExpress (MCE) BAY-3827

More
Customer Validation & Images
In Vivo Efficacy StudyWBHistological Imaging/StainingRT-PCRELISA
  • In Vivo Efficacy Study
  • Histological Imaging/Staining
  • ELISA
  • WB
  • RT-PCR

All AMPK Isoforms

More
Keywords
MOQ
Minimum order quantity
100 mg

견적 받기 해외재고보유

Other size
견적 받기
Please select quantity
Amount: USD 0.00
Sign in to MedChemExpress 로그인
Register
Sign in to MedChemExpress
회원가입

At least 6 characters

Personalize your experience, you are currently not signed in. For a better experience, please create an online profile, you can:

Obtain points redemption prizes
Check out faster
Add multiple shipping locations
View orders
Assay Types
  • BAY-3827 Chemical Structure
    BAY-3827 Chemical Structure
    1/16
  • 1/16

    BAY-3827 purchased from MedChemExpress. Usage Cited in: J Pharm Anal. 2025 Dec 15.

    Customer Validation
     BAY-3827 at 10 mg/kg for a duration of 4 weeks. Distinctive micro-CT visuals showcasing both longitudinal and cross-sectional views of the distal femur segments.

  • 1/16

    BAY-3827 purchased from MedChemExpress. Usage Cited in: J Pharm Anal. 2025 Dec 15.

    Customer Validation
     BAY-3827 was administered at 10 mg/kg for a duration of 4 weeks. Representative images of hematoxylin and eosin (H&E) staining and Masson's staining of the metaphyseal tissue sections of the thigh were presented.

  • 1/16

    BAY-3827 purchased from MedChemExpress. Usage Cited in: J Agric Food Chem. 2025 Dec 22. [Abstract]

    Customer Validation
     ELISA quantification of IL-1β in BMDM supernatants following LPS + nigericin stimulation with or without Api, the AMPK agonist AICAR, or the AMPK inhibitor BAY-3827 (500 nM) was performed.

  • 1/16

    BAY-3827 purchased from MedChemExpress. Usage Cited in: Int J Mol Sci. 2025 Oct 16;26(20):10098. [Abstract]

    Customer Validation
     HCFs were incubated with the AMPK inhibitor BAY-3827 (500 nM) for 1 h prior to stimulation with DMSO (vehicle) or indicated concentrations of SGLT2i for 3 h.

  • 1/16

    BAY-3827 purchased from MedChemExpress. Usage Cited in: Int J Mol Sci. 2025 Oct 16;26(20):10098. [Abstract]

    Customer Validation
     HCFs were incubated with the AMPK inhibitor BAY-3827 (500 nM) for 1 h prior to stimulation with DMSO (vehicle) or indicated concentrations of SGLT2i for 72 h.

  • BAY-3827