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Cat. No.: HY-184418

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CDK4-IN-6

CDK4-IN-6 is a CDK4 inhibitor with an IC₅₀ of 0.0011 μM. CDK4-IN-6 can be used for the research of breast cancer.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 3120500-44-6
화학식: C₂₀H₂₉FN₆O₃S
분자량:452.55

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

CDK4-IN-6 Chemical Structure

CAS No.: 3120500-44-6

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
Protocol (2)
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

CDK4-IN-6 is a CDK4 inhibitor with an IC₅₀ of 0.0011 μM. CDK4-IN-6 can be used for the research of breast cancer^[1].

IC₅₀ & Target

^[1]

CDK4

0.0011 μM (IC₅₀)

All CDK Isoforms :

In Vitro

CDK4-IN-6 (compound 95) inhibits human CDK4 with an IC₅₀ of 0.0011 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.

Chemical Information

CAS No. 3120500-44-6
분자량 452.55
화학식 C₂₀H₂₉FN₆O₃S
SMILES

O[C@H](CN(S(=O)(C)=O)CC1)[C@@H]1NC2=NC=C3C(N([C@@H]4CCNC[C@@H]4F)C(C5CC5)=C3)=N2
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocol

All Cell Biology Animals and Diseases

Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Breast Cancer Modeling
Breast cancer is a heterogeneous cancer, and it has been distinguished into four subtypes: luminal A, luminal B, HER2-positive and basal-like. Molecular mutations, epigenetic alterations, hormone exposure and immune microenvironment are related to the progression of breast cancer.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Sabnis R W. Novel Compounds as CDK4 Inhibitors for Treating Breast Cancer. ACS Medicinal Chemistry Letters. 2026.

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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