Colchiceine
Based on 1 Customer Validation
Colchiceine is one of several metabolites of the anti-gout medication Colchicine (HY-16569). Colchicine is a tubulin inhibitor and a microtubule disrupting agent, and may protect rats from developing liver injury and fibrosis.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 477-27-0
- 화학식: C21H23NO6
- 분자량:385.41
-
보관:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- 순도&문서
- References
-
Help & FAQs
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
0.002 μg/mL
Compound: 1
|
In vitro cytotoxic activity against human lung carcinoma (A549) tumor cell line
In vitro cytotoxic activity against human lung carcinoma (A549) tumor cell line
|
[PMID: 15582446] |
Chemical Information
-
CAS No. 477-27-0
-
Appearance Solid
-
분자량 385.41
-
화학식 C21H23NO6
-
Color Off-white to light yellow
-
SMILES
CC(N[C@H](C1=C2)CCC3=CC(OC)=C(OC)C(OC)=C3C1=CC=C(O)C2=O)=O
-
Synonyms
O10-Demethylcolchicine
-
Structure Classification
-
Initial Source
-
선적
Room temperature in continental US; may vary elsewhere.
-
보관
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
순도&문서
-
Data Sheet (276 KB)
-
SDS (477 KB)
- English - EN (477 KB)
- Français - FR (477 KB)
- Deutsch - DE (477 KB)
- Norwegian - NO (477 KB)
- Español - ES (477 KB)
- Swedish - SV (477 KB)
- Italian - IT (477 KB)
- Korean - KR (477 KB)
- Portuguese - PT (477 KB)
-
Handling Instructions (2659 KB)
References
[1]. Rodríguez L, et al. Effects of colchicine and colchiceine in a biochemical model of liver injury and fibrosis. Arch Med Res. 1998;29(2):109-116. [Content Brief]
[2]. Nava-Ocampo AA, et al. Effect of colchiceine and ursodeoxycholic acid on hepatocyte and erythrocyte membranes and liver histology in experimentally induced carbon tetrachloride cirrhosis in rats. Eur J Clin Invest. 1997;27(1):77-84. [Content Brief]
[3]. Edström A, et al. Inhibition of fast axonal transport and microtubule polymerization in vitro by colchicine and colchiceine. Acta Physiol Scand. 1979;107(3):233-237. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Colchiceine Related Classifications
HY-127166 Related Classifications
Powered by Bioz