Coronalolide
Coronalolide is a natural triterpene with anticancer effects. Coronalolide exhibits a broad cytotoxic activity for human breast (BT474), gastric (KATO-3), lung (CHAGO), colon (SW-620), and liver (Hep-G2) cancer cell lines, with IC50 values of 6.59 µg/mL, 5.85 µg/mL, 5.42 µg/mL, 4.98 µg/mL, and 6.41 µg/mL, respectively.
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- CAS No.: 268214-51-3
- 화학식: C30H42O5
- 분자량:482.65
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| BT-474 | IC50 |
6.59 μg/mL
Compound: 7
|
Cytotoxicity against human BT474 cells after 3 days by MTT assay
Cytotoxicity against human BT474 cells after 3 days by MTT assay
|
[PMID: 19456120] |
| HepG2 | IC50 |
6.41 μg/mL
Compound: 7
|
Cytotoxicity against human HepG2 cells after 3 days by MTT assay
Cytotoxicity against human HepG2 cells after 3 days by MTT assay
|
[PMID: 19456120] |
| SW-620 | IC50 |
4.98 μg/mL
Compound: 7
|
Cytotoxicity against human SW620 cells after 3 days by MTT assay
Cytotoxicity against human SW620 cells after 3 days by MTT assay
|
[PMID: 19456120] |
Chemical Information
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CAS No. 268214-51-3
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분자량 482.65
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화학식 C30H42O5
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SMILES
OC(CC[C@@]12[C@]3([C@](C[C@](O4)([H])[C@@]2([H])C(C4=O)=C)([H])[C@]5([C@@](C)([C@]([C@H](C)CC/C=C(C)/C=O)([H])CC5)CC3)C)C1)=O
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Structure Classification
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Initial Source
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)