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Cat. No.: HY-117767

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CZ830

CZ830 is a mTOR kinase inhibitor with an IC₅₀ of < 1 μM. CZ830 is applicable to the research of collagen-induced arthritis.

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CAS No.: 1333108-58-9
화학식: C₂₅H₂₆F₃N₅O₄S
분자량:549.57

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

CZ830 Chemical Structure

CAS No.: 1333108-58-9

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

CZ830 is a mTOR kinase inhibitor with an IC₅₀ of < 1 μM. CZ830 is applicable to the research of collagen-induced arthritis^[1].

All mTOR Isoforms :

In Vitro

CZ830 inhibits mTOR kinase activity with an IC₅₀ of <1 μM, forming specific hydrogen bonds with key mTOR residues Asp2195, Asp2357, and Val2240^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1333108-58-9
분자량 549.57
화학식 C₂₅H₂₆F₃N₅O₄S
SMILES

S(C)(=O)(=O)C1=C(C2=NC(=NC(=C2)C3=CC=C(NC(NCC(F)F)=O)C=C3)N4[C@@H](C)COCC4)C=C(F)C=C1
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Xu T, et al. Targeting mTOR for fighting diseases: A revisited review of mTOR inhibitors. Eur J Med Chem. 2020;199:112391. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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