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Cat. No.: HY-107176

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(E)-Hyzetimibe

(Synonyms: (E)-HS-25)

(E)-Hyzetimibe ((E)-HS-25) (Compound I-1Z) is the trans isomer of Hyzetimibe (HY-107176A), a cholesterol-lowering agent. (E)-Hyzetimibe has cholesterol acyltransferase (ACTA) inhibitory activity, but its cholesterol-lowering effect is relatively weak. (E)-Hyzetimibe can inhibit the entry of hepatitis C virus (HCV) into host cells, and it has a synergistic effect when used in combination with interferon-α. (E)-Hyzetimibe can be used for the study of HCV infection.

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CAS No.: 1266548-75-7
화학식: C₂₅H₂₁F₂NO₃
분자량:421.44

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

(E)-Hyzetimibe Chemical Structure

CAS No.: 1266548-75-7

사이즈

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수량

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

All Acyltransferase Isoforms :

Chemical Information

CAS No. 1266548-75-7
분자량 421.44
화학식 C₂₅H₂₁F₂NO₃
SMILES

OC/C(C1=CC=C(C=C1)F)=C/C[C@@H]2[C@@H](C3=CC=C(C=C3)O)N(C4=CC=C(C=C4)F)C2=O
Synonyms

(E)-HS-25
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. BAI Y, et al. Azetidinone compound used for prevention and/or treatment of hepatitis c, and composition of the compound. WO2014131371A1

[2]. BAI Y, et al. Azetidinone compounds and medical use thereof. WO2011017907.

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

상품명:
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(E)-Hyzetimibe

All Acyltransferase Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

(E)-Hyzetimibe Related Classifications

HY-107176 Related Classifications