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Cat. No.: HY-N19772

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Echiguanine B

Echiguanine B is a phosphatidylinositol-4-kinase (PI4K) inhibitor with an IC₅₀ of 0.11 μg/mL against human targets. Echiguanine B inhibits phosphatidylinositol-4-kinase activity in the cell membranes of epithelial cancer cells. Echiguanine B can be used in cancer-related research.

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CAS No.: 137319-26-7
화학식: C₁₀H₁₄N₆O₂
분자량:250.26

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Echiguanine B Chemical Structure

CAS No.: 137319-26-7

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References
Calculators
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Bioz

Biological Activity

제품 설명

IC₅₀ & Target^[1]

PI4K

0.11 μg/mL (IC₅₀)

All PI4K Isoforms :

In Vitro

Echiguanine B (20 min at 20°C) inhibits phosphatidylinositol-4-kinase from A431 cell membranes with an IC₅₀ of 0.11 μg/mL^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 137319-26-7
분자량 250.26
화학식 C₁₀H₁₄N₆O₂
SMILES

O=C1N=C(NC2=C1C(C(NCCCN)=O)=CN2)N
Structure Classification
- Others
Initial Source
- Microorganisms
STREPTOMYCES SP.
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Nishioka H, et al. Isolation and structure determination of novel phosphatidylinositol kinase inhibitors, echiguanines A and B, from Streptomyces sp. Journal of natural products. 1991;54(5):1321-5. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
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- IC₅₀ & Target
- In Vitro
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Echiguanine B

All PI4K Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Echiguanine B Related Classifications

HY-N19772 Related Classifications