Eucatropine
Eucatropine is a potent muscarinic acetylcholine receptor (mAChR) inhibitor with an IC50 value of 0.583 μM. Eucatropine acts as an anticholinergic agent. Eucatropine produces behavioral effects via central cholinergic receptive sites in cats.
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- CAS No.: 100-91-4
- 화학식: C17H25NO3
- 분자량:291.39
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male and female (2-4 kg; intracerebroventricular cannula implantation)[1]
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Dosage:0.2 mg, 0.5 mg, 1.0 mg, 2.0 mg
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Administration:i.c.v.; single injection
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Result:Produced inconsistent emotional effects including miaowing, loud calling, loss of interest of the surroundings, rage, threat, attack, defense, fighting with paws, and flight; no restlessness, impelling locomotion, vacant staring, or apprehension.
Caused consistent mydriasis and tachypnea; inconsistent dyspnea, licking, vomiting, salivation, defecation, and micturition.
Induced consistent ataxia; no scratching, rigidity, weakness with adynamia, myoclonic jerks, or convulsions.
Showed no measurable impelling locomotion at any tested dose.
Caused very short-duration, non-dose-dependent aggressive fighting behavior with mean duration near 0 minutes across all tested doses.
Chemical Information
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CAS No. 100-91-4
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분자량 291.39
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화학식 C17H25NO3
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SMILES
O=C(OC1CC(C)(C)N(C)C(C)C1)C(O)C2=CC=CC=C2
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
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Data Sheet (270 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Beleslin DB, et al. Comparative behavioral effects of anticholinergic agents in cats: psychomotor stimulation and aggression. Pharmacol Biochem Behav. 1986;24(3):581-586. [Content Brief]
[2]. Schmeller T, et, al. Binding of tropane alkaloids to nicotinic and muscarinic acetylcholine receptors. Pharmazie. 1995 Jul;50(7):493-5. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Eucatropine Related Classifications
HY-117284 Related Classifications
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