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Cat. No.: HY-189099

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G2iA

G2iA is a selective GLUT2 inhibitor that inhibits GLUT2-mediated glucose transport with an IC₅₀ of 0.61 µM.

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CAS No.: 536702-12-2
화학식: C₂₇H₂₄FN₃O₂S
분자량:473.56

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

G2iA Chemical Structure

CAS No.: 536702-12-2

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

G2iA is a selective GLUT2 inhibitor that inhibits GLUT2-mediated glucose transport with an IC₅₀ of 0.61 µM^[1].

IC₅₀ & Target

^[1]

GLUT2

0.61 μM (IC₅₀)

All GLUT Isoforms :

In Vitro

Carbohydrate Metabolism

G2iA inhibits glucose uptake via human GLUT2∆loopS_Q455R expressed in the hxt0 yeast strain EBY.S7, with an IC₅₀ of 0.61 µM, and acts as a noncompetitive inhibitor with respect to glucose^[1].
G2iA (100 µM; 10 min) is a GLUT2-selective inhibitor that, at a concentration of 100 µM, does not significantly inhibit GLUT1, GLUT3, GLUT4, or GLUT5 in hxt0 yeast transport assays^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 536702-12-2
분자량 473.56
화학식 C₂₇H₂₄FN₃O₂S
SMILES

O=C(CSC1=C(C)NC2=C1C=CC=C2)N3N=C(CC3C4=CC=C(C=C4)F)C5=CC=C(OC)C=C5
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Schmidl S, et al. Identification of new GLUT2-selective inhibitors through in silico ligand screening and validation in eukaryotic expression systems. Scientific reports. 2021 Jul 02;11(1):13751.

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

견적 받기 해외재고보유

Other size

견적 받기

Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
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CAS No.:
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수량:

G2iA

All GLUT Isoforms

Biological Activity

제품 설명

IC50 & Target

In Vitro

Chemical Information

순도&문서

References

Calculators

Help & FAQs

G2iA Related Classifications

HY-189099 Related Classifications

Bioz

Keywords

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