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Cat. No.: HY-124919

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JJO-1

JJO-1 is an AMPK activator with an EC₅₀ of 1.8 μM. JJO-1 can be used in the study of obesity and type 2 diabetes.

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CAS No.: 16722-44-4
화학식: C₁₉H₁₃N₃
분자량:283.33

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

JJO-1 Chemical Structure

CAS No.: 16722-44-4

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

JJO-1 is an AMPK activator with an EC₅₀ of 1.8 μM. JJO-1 can be used in the study of obesity and type 2 diabetes^[1].

All AMPK Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
COS-7	EC₅₀	1.8 μM Compound: 29	Activation of human recombinant AMPK GST-tagged alpha1/Myc-tagged beta1/HA-tagged gamma1 expressed in African green monkey COS7 cells assessed as increase in SAMS peptide phosphorylation measured after 10 mins in presence of [gamma33P]ATP by scintillation Activation of human recombinant AMPK GST-tagged alpha1/Myc-tagged beta1/HA-tagged gamma1 expressed in African green monkey COS7 cells assessed as increase in SAMS peptide phosphorylation measured after 10 mins in presence of [gamma33P]ATP by scintillation	[PMID: 27727125]

Chemical Information

CAS No. 16722-44-4
분자량 283.33
화학식 C₁₉H₁₃N₃
SMILES

C1(/C=N/C2=CN=C3C=CC=CC3=C2)=CC=C4C=CC=CC4=N1
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Scott JW, Oakhill JS, Ling NX, Langendorf CG, Foitzik RC, Kemp BE, Issinger OG. ATP sensitive bi-quinoline activator of the AMP-activated protein kinase. Biochem Biophys Res Commun. 2014 Jan 10;443(2):435-40. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

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JJO-1

All AMPK Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

JJO-1 Related Classifications

HY-124919 Related Classifications