LM-41
Based on 1 Customer Validation
LM-41 is a Flufenamic acid-derived TEAD inhibitor hat strongly reduce the expression of CTGF, Cyr61, Axl and NF2. LM-41 inhibits migration of human MDA-MB-231 breast cancer cells.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity : 99.87%
- CAS No.: 2996821-30-6
- 화학식: C19H14FNO2
- 분자량:307.32
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보관:
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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용액&용해도
- Protocol
- 순도&문서
- References
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Help & FAQs
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Biological Activity
제품 설명
Chemical Information
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CAS No. 2996821-30-6
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Appearance Solid
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분자량 307.32
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화학식 C19H14FNO2
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Color White to off-white
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SMILES
OC(C1=CC=C(F)C=C1NC2=CC(C3=CC=CC=C3)=CC=C2)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
용액&용해도
In Vitro:
DMSO : 140 mg/mL (455.55 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Protocol
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RNA extraction experimental
By lysing cells, releasing RNA, and removing impurities such as proteins and DNA, high-purity RNA products are finally obtained. The commonly used traditional method is the guanidine isothiocyanate/phenol/chloroform method (Trizol), which is suitable for a variety of animal materials including animal tissues, microorganisms, cultured cells, etc., and most plant materials.
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Cell migration
Cell migration is a method that plays an important role in wound healing, cell differentiation, embryonic development, etc.
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Breast Cancer Modeling
Breast cancer is a heterogeneous cancer, and it has been distinguished into four subtypes: luminal A, luminal B, HER2-positive and basal-like. Molecular mutations, epigenetic alterations, hormone exposure and immune microenvironment are related to the progression of breast cancer.
순도&문서
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Data Sheet (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.2539 mL | 16.2697 mL | 32.5394 mL | 81.3484 mL |
| 5 mM | 0.6508 mL | 3.2539 mL | 6.5079 mL | 16.2697 mL | |
| 10 mM | 0.3254 mL | 1.6270 mL | 3.2539 mL | 8.1348 mL | |
| 15 mM | 0.2169 mL | 1.0846 mL | 2.1693 mL | 5.4232 mL | |
| 20 mM | 0.1627 mL | 0.8135 mL | 1.6270 mL | 4.0674 mL | |
| 25 mM | 0.1302 mL | 0.6508 mL | 1.3016 mL | 3.2539 mL | |
| 30 mM | 0.1085 mL | 0.5423 mL | 1.0846 mL | 2.7116 mL | |
| 40 mM | 0.0813 mL | 0.4067 mL | 0.8135 mL | 2.0337 mL | |
| 50 mM | 0.0651 mL | 0.3254 mL | 0.6508 mL | 1.6270 mL | |
| 60 mM | 0.0542 mL | 0.2712 mL | 0.5423 mL | 1.3558 mL | |
| 80 mM | 0.0407 mL | 0.2034 mL | 0.4067 mL | 1.0169 mL | |
| 100 mM | 0.0325 mL | 0.1627 mL | 0.3254 mL | 0.8135 mL |
LM-41 Related Classifications
HY-155309 Related Classifications
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