LTB
LTB is a prodrug formed by coupling glycolysis inhibitor (Lonidamine (HY-B0486)) with PD1/PDL1 blocker (BMS-1 (HY-19991)) by thioketal linkage. LTB can further encapsulate photosensitizer chlorine e6 (Ce6) (HY-13594) to construct a co-delivery photodynamic nanoplatform (LTB-6 NPs) by self-assembly.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- 화학식: C53H59Cl2N3O7S2
- 분자량:985.09
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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분자량 985.09
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화학식 C53H59Cl2N3O7S2
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SMILES
COC1=CC(OCC2=C(C(C3=CC=CC=C3)=CC=C2)C)=CC(OC)=C1CN4CCCC[C@H]4C(OCCCSC(C)(SCCCOC(C5=NN(C6=C5C=CC=C6)CC7=CC=C(C=C7Cl)Cl)=O)C)=O
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Synonyms
Lon-TK-BMS-1
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
LTB Related Classifications
HY-169434 Related Classifications
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