LX2932
LX2932 is an orally active LX2931 (HY-14370) analogue and S1P/S1PR signaling axis modulator. LX2932 yields a dose-dependent decrease in circulating lymphocyte numbers. LX2932 improves collagen-induced arthritis.
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- CAS No.: 1055027-48-9
- 화학식: C10H13N3O5
- 분자량:255.23
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 1055027-48-9
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분자량 255.23
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화학식 C10H13N3O5
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SMILES
[C@@H]([C@@H]([C@@H](CO)O)O)(O)C=1NC(=NC1)C=2C=CON2
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Bagdanoff JT, et al. Inhibition of sphingosine 1-phosphate lyase for the treatment of rheumatoid arthritis: discovery of (E)-1-(4-((1R,2S,3R)-1,2,3,4-tetrahydroxybutyl)-1H-imidazol-2-yl)ethanone oxime (LX2931) and (1R,2S,3R)-1-(2-(isoxazol-3-yl)-1H-imidazol-4-yl)butane-1,2,3,4-tetraol (LX2932). J Med Chem. 2010 Dec 23;53(24):8650-62. [Content Brief]
[2]. Gao Y, et al. Rheumatoid arthritis: pathogenesis and therapeutic advances. MedComm (2020). 2024 Mar 10;5(3):e509. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
LX2932 Related Classifications
HY-14371 Related Classifications
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