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Cat. No.: HY-123575

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LY 245769

LY 245769, a omega-trifluoro analog, is a leukotriene E4 (LTE4) inhibitor. LY 245769 interfers the omega-oxidation of N-acetyl-LTE4 and leukotriene B4 (LTB4) with IC₅₀s of 4 μM.

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CAS No.: 127345-02-2
화학식: C₂₅H₃₃F₃N₈OS
분자량:550.64

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

LY 245769 Chemical Structure

CAS No.: 127345-02-2

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

LY 245769, a omega-trifluoro analog, is a leukotriene E4 (LTE4) inhibitor. LY 245769 interfers the omega-oxidation of N-acetyl-LTE4 and leukotriene B4 (LTB4) with IC₅₀s of 4 μM^[1].

All Leukotriene Receptor Isoforms :

Chemical Information

CAS No. 127345-02-2
분자량 550.64
화학식 C₂₅H₃₃F₃N₈OS
SMILES

O[C@@H](C1=CC=CC(C2=NN=NN2)=C1)[C@@H](/C=C/C=C\CCCCCCCCC(F)(F)F)SCCC3=NN=NN3
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. G Jedlitschky, et al. Inhibition of leukotriene omega-oxidation by omega-trifluoro analogs of leukotrienes. Arch Biochem Biophys. 1990 Nov 1;282(2):333-9. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biological Activity
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Chemical Information
순도&문서
References

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LY 245769

All Leukotriene Receptor Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

LY 245769 Related Classifications

HY-123575 Related Classifications