Mezlocillin
Mezlocillin (BAY-f 1353) is a β-lactam antibiotic, a semisynthetic and extended-spectrum antibiotic. Mezlocillin is active against both gram-negative and gram-positive bacteria. Mezlocillin can be used in bacterial infection research.
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- CAS No.: 51481-65-3
- 화학식: C21H25N5O8S2
- 분자량:539.58
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
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Biological Activity
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β-lactam |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male Balb/c mice[1]
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Dosage:1.7, 4.3, and 5.7 mg/kg
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Administration:Subcutaneous injection; 1.7, 4.3, and 5.7 mg/kg; twice daily; 7 days
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Result:Suppressed the IgM and IgG responses and the delayed-type hypersensitivity reaction treated with all doses.
Observed a loss of hair in the majority of animals treated with all doses.
Inhibited lymphocyte proliferation of spleen-cell cultures from animals.
Chemical Information
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CAS No. 51481-65-3
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분자량 539.58
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화학식 C21H25N5O8S2
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SMILES
O=C([C@@H](C(C)(C)S[C@]1([H])[C@@H]2NC([C@H](NC(N3CCN(S(=O)(C)=O)C3=O)=O)C4=CC=CC=C4)=O)N1C2=O)O
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Synonyms
BAY-f 1353
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Roszkowski W, et al. Antibiotics and immunomodulation: effects of cefotaxime, amikacin, mezlocillin, piperacillin and clindamycin. Med Microbiol Immunol. 1985;173(5):279-89. [Content Brief]
[2]. Bodey GP, et al. Mezlocillin: in vitro studies of a new broad-spectrum penicillin. Antimicrob Agents Chemother. 1977 Jan;11(1):74-9. [Content Brief]
[3]. Kristof RA, et al. Treatment of accidental high dose intraventricular mezlocillin application by cerebrospinal fluid exchange. J Neurol Neurosurg Psychiatry. 1998 Mar;64(3):379-81. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Mezlocillin Related Classifications
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