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Cat. No.: HY-N16715

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Monardic acid A

Monardic acid A is a selective inhibitor of AChE, with an IC₅₀ of 53.1 μM against AChE from electric eel. Monardic acid A shows weak inhibitory activity against human erythrocyte AChE (IC₅₀ >100 μM) and has no significant inhibitory effect on BChE. Monardic acid A reduces acetylcholine breakdown by inhibiting AChE activity, and also exhibits inhibitory activity against histamine release and hyaluronidase, thus exerting anti-inflammatory and neurotransmitter regulatory effects. Monardic acid A can be isolated from lungwort (Pulmonaria officinalis) and thyme (Thymus gobicus), and is mainly used in the development of anti-inflammatory drugs and drugs related to neurodegenerative diseases.

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CAS No.: 1607436-76-9
화학식: C₂₇H₂₂O₁₂
분자량:538.46

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

Monardic acid A Chemical Structure

CAS No.: 1607436-76-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Bioz

Biological Activity

제품 설명

IC₅₀ & Target

AChE

All Cholinesterase (ChE) Isoforms :

AChE
BChE

Chemical Information

CAS No. 1607436-76-9
분자량 538.46
화학식 C₂₇H₂₂O₁₂
SMILES

OC([C@@H]1C2=C(/C=C/C(O[C@@H](C(O)=O)CC3=CC(O)=C(C=C3)O)=O)C=CC(O)=C2O[C@H]1C4=CC(O)=C(C=C4)O)=O
Structure Classification
- Phenylpropanoids
- Lignans
Initial Source
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Krzyżanowska-Kowalczyk J, et al. Novel Phenolic Constituents of Pulmonaria officinalis L. LC-MS/MS Comparison of Spring and Autumn Metabolite Profiles. Molecules. 2018 Sep 6;23(9):2277. [Content Brief]

[2]. Odonbayar B, et al. Chemical constituents of aerial parts of Thymus gobicus and their cholinesterase inhibitory activities[J]. Mongolian Journal of Chemistry, 2016, 17(43): 14-17.

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Monardic acid A

All Cholinesterase (ChE) Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Monardic acid A Related Classifications

HY-N16715 Related Classifications