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Cat. No.: HY-125636

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Mycro1

Mycro1 is an inhibitor of c-Myc/Max dimer and DNA binding, with an IC₅₀ value of 30 μM for the inhibition of Myc/Max DNA binding activity. Mycro1 can inhibit c-myc-dependent cell proliferation, gene transcription and oncogenic transformation.

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CAS No.: 313987-85-8
화학식: C₂₀H₁₅F₃N₄O₂S
분자량:432.42

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Mycro1 Chemical Structure

CAS No.: 313987-85-8

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

In Vitro

Mycro1 (10 or 20 μM, 7 days) can inhibit the proliferation of C-Myc-dependent cell lines U-2OS, MCF-7, Raji and NIH/3T3, but does not inhibit the proliferation of C-Myc-independent cancer cell line PC-12. Mycro1 significantly inhibits c-myc-induced gene transcription at 10 μM and selectively reduces unanchored growth of c-myc-transformed Rat1a cells at 20 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 313987-85-8
분자량 432.42
화학식 C₂₀H₁₅F₃N₄O₂S
SMILES

O=C(NCC1=CC=C(C=C1)OC)C2=NN3C(C(F)(F)F)=CC(C4=CC=CS4)=NC3=C2
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Kiessling A, et al. Selective inhibition of c-Myc/Max dimerization and DNA binding by small molecules. Chem Biol. 2006 Jul;13(7):745-51. [Content Brief]

[2]. Anke Kiessling, et al. Selective inhibition of c-Myc/Max dimerization and DNA binding by small molecules. Chem Biol. 2006 Jul;13(7):745-51.

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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