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Cat. No.: HY-19088

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Oberadilol

(Synonyms: CID-3047798)

Oberadilol (CID-3047798) is a Phosphodiesterase III inhibitor, non-selective β-adrenergic receptor blocker, vasodilator and positive inotropic agent. Oberadilol reduces left ventricular end-diastolic volume. Oberadilol is used in research related to chronic congestive heart failure and SARS-CoV-2 infection.

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CAS No.: 114856-44-9
화학식: C₂₅H₃₀ClN₅O₃
분자량:483.99

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

Oberadilol Chemical Structure

CAS No.: 114856-44-9

사이즈

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수량

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

IC₅₀ & Target^[1]

PDE Ⅲ

β adrenergic receptor

All Phosphodiesterase (PDE) Isoforms :

All Adrenergic Receptor Isoforms :

In Vitro

Oberadilol is a pyridazinone derivative with vasodilatory, β-adrenergic blocking, and type III phosphodiesterase inhibitory activities^[1].
Oberadilol reduces left ventricular end-diastolic volume and tends to increase ejection fraction^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 114856-44-9
분자량 483.99
화학식 C₂₅H₃₀ClN₅O₃
SMILES

N#CC1=CC=C(Cl)C=C1OCC(O)CNC(C)(C)CNC2=CC=C(C(C(C)C3)=NNC3=O)C=C2
Synonyms

CID-3047798
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Araki S, et al. Cardiac and hemodynamic effects of TZC-5665, a novel pyridazinone derivative, and its metabolite in humans and dogs. General pharmacology. 1997 Apr;28(4):545-53. [Content Brief]

[2]. Asif M. The biological potentials of substituted 1, 2-diazines: A review on versatile pyridazine derivatives[J]. Journal of Chinese Pharmaceutical Sciences, 2016, 25(10): 707.

[3]. Srivastava A, et al. Exploring nature's bounty: identification of Withania somnifera as a promising source of therapeutic agents against COVID-19 by virtual screening and in silico evaluation. J Biomol Struct Dyn. 2022 Mar;40(4):1858-1908. [Content Brief]

[4]. Imran M, et al. Study of various pyridazine and phthalazine drugs with diverse therapeutical and agrochemical activities[J]. Russian Journal of Bioorganic Chemistry, 2020, 46(5): 745-767.

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References

상품명:
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수량:
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Oberadilol

All Phosphodiesterase (PDE) Isoforms

All Adrenergic Receptor Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Oberadilol Related Classifications

HY-19088 Related Classifications