Parvisoflavone B
Parvisoflavone B is a prenylated flavonoid. Parvisoflavone B can be isolated from root bark of Erythrina mildbraedii. Parvisoflavone B inhibits PTP1B activity with an IC50 of 42.6 μM. Parvisoflavone B inhibits α-glucosidase with an IC50 of 12.19 μM. Parvisoflavone B can be used in the research of type 2 diabetes and obesity.
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- CAS No.: 50277-02-6
- 화학식: C20H16O6
- 분자량:352.34
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
제품 설명
IC50 & Target
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MDA-MB-231 | EC50 |
16.9 μM
Compound: 16
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Cytotoxicity against human MDA-MB-231 cells
Cytotoxicity against human MDA-MB-231 cells
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[PMID: 28112509] |
Chemical Information
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CAS No. 50277-02-6
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분자량 352.34
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화학식 C20H16O6
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SMILES
O=C1C(=COC2=CC=3OC(C=CC3C(O)=C12)(C)C)C=4C=CC(O)=CC4O
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Structure Classification
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Initial Source
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Jang J, et al. Prenylated flavonoids with PTP1B inhibitory activity from the root bark of Erythrina mildbraedii. Chem Pharm Bull (Tokyo). 2008 Jan;56(1):85-8. [Content Brief]
[2]. Dendup T, et al. α-Glucosidase inhibitory activities of isoflavanones, isoflavones, and pterocarpans from Mucuna pruriens. Planta Med. 2014 May;80(7):604-8. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Parvisoflavone B Related Classifications
HY-N17601 Related Classifications
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