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Cat. No.: HY-N19846

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Pithecolobine

Pithecolobine is a saponin-like alkaloid found in the bark, seeds, and leaves of Samanea saman. Pithecolobine can inhibit the growth of Gram-positive bacteria, Gram-negative bacteria, and pathogenic yeasts. Pithecolobine scavenges DPPH radicals. Pithecolobine can be used for the research of infections caused by pathogenic bacteria and yeasts.

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CAS No.: 22368-82-7
화학식: C₂₂H₄₆N₄O₂
분자량:398.63

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Pithecolobine Chemical Structure

CAS No.: 22368-82-7

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

In Vitro

Pithecolobine (0.25 mg/disc) exhibits concentration-dependent antimicrobial activity against Escherichia coli NCIM 2065, Klebsiella pneumoniae NCIM 2957, Proteus vulgaris NCIM 2027, Pseudomonas aeruginosa NCIM 5031, Salmonella typhi NCIM 2051, Staphylococcus aureus NCIM 2079, Streptococcus faecalis NCIM 5025, Candida albicans NCIM 3471, and Cryptococcus neoformans NCIM 3541^[2].
Pithecolobine (0.95-1000 μg/mL; 24-48 h) inhibits and kills Escherichia coli NCIM 2065, Klebsiella pneumoniae NCIM 2957, Proteus vulgaris NCIM 2027, Pseudomonas aeruginosa NCIM 5031, Salmonella typhi NCIM 2051, Staphylococcus aureus NCIM 2079, Streptococcus faecalis NCIM 5025, Candida albicans NCIM 3471, and Cryptococcus neoformans NCIM 3541^[2].
Pithecolobine (31-1000 μg/mL; 30 min) scavenges DPPH radicals with an IC₅₀ of 250 μg/mL in a cell-free in vitro assay^[2].
Pithecolobine (1000 μg/mL; 2 h) inhibits β-Carotene (HY-N0411)/Linoleic acid (HY-N0729) bleaching by 70.4% at a concentration of 1000 μg/mL in a cell-free in vitro assay^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 22368-82-7
분자량 398.63
화학식 C₂₂H₄₆N₄O₂
SMILES

O=C1NCCCN(CCCCNCCCNC(CCCCCCC)CCC1)O
Structure Classification
- Others
Initial Source
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Harismah K, et al. Formulation and Evaluation of Herbal Hand Sanitizer Based on Stevia (Stevia rebaudiana). J. Phys. Conf. Ser. 2021;1858:012053.

[2]. Thippeswamy S, et al. Evaluation of Antimicrobial and Antioxidant Properties of Pithecolobine Isolated from Albizia saman. J Herbs Spices Med P. 2015 Jul 09;21:438-446.

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

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Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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