PPI stabilizer-1
PPI stabilizer-1-1 (Compound 2) is a KRAS dimerizing agent. PPI stabilizer-1-1 dimerizes KRAS with a KD of 3.8 µM. PPI stabilizer-1-1 co-crystallizes with GCP-KRASG12D. PPI stabilizer-1 can be used for the research of KRAS-driven cancers.
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- CAS No.: 2429876-60-6
- 화학식: C40H40N6O4
- 분자량:668.78
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
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KRas G12D |
PPI stabilizer-1 dimerizes KRAS with a KD of 3.8 µM according to isothermal calorimetry measurements[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2429876-60-6
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분자량 668.78
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화학식 C40H40N6O4
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SMILES
O=C(N1)C(C([C@H]1C(C2=CC=CC=C2N3)=C3CNCCCCCCNCC4=C([C@@H]5C6=CC(O)=CC=C6C(N5)=O)C7=CC=CC=C7N4)=C8)=CC=C8O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PPI stabilizer-1 Related Classifications
HY-185217 Related Classifications
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