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Cat. No.: HY-149299

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PYZ18

PYZ18 is a selective COX-2 inhibitor with an IC₅₀ of 7.07 μM. PYZ18 is the best lead compound for COX-2 inhibitors. PYZ18 has anti-inflammatory and other biological properties.

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CAS No.: 1447578-01-9
화학식: C₁₈H₁₄F₃N₃S
분자량:361.38

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

PYZ18 Chemical Structure

CAS No.: 1447578-01-9

사이즈

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수량

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

PYZ18 is a selective COX-2 inhibitor with an IC₅₀ of 7.07 μM. PYZ18 is the best lead compound for COX-2 inhibitors. PYZ18 has anti-inflammatory and other biological properties^[1].

IC₅₀ & Target^[1]

COX-2

7.07 μM (IC₅₀)

All COX Isoforms :

Chemical Information

CAS No. 1447578-01-9
분자량 361.38
화학식 C₁₈H₁₄F₃N₃S
SMILES

FC(F)(C1=NN(C(C2=CC=C(C)C=C2)=C1)C3=CC=C(C(N)=S)C=C3)F
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Chahal S, et al. Design and Development of COX-II Inhibitors: Current Scenario and Future Perspective. ACS Omega. 2023 May 9;8(20):17446-17498 [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
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상품명:
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PYZ18

All COX Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

PYZ18 Related Classifications

HY-149299 Related Classifications