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Cat. No.: HY-P12340

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RAYZ-8009

RAYZ-8009 is a DOTA (HY-W053583)-modified macrocyclic peptide with high affinity for GPC3. The radiolabeled form of RAYZ-8009, [⁶⁸Ga]Ga-RAYZ-8009, is used for PET imaging studies of hepatocellular carcinoma.

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CAS No.: 3066113-06-9
화학식: C₉₁H₁₁₉N₁₇O₂₂S
분자량:1835.08

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

RAYZ-8009 Chemical Structure

CAS No.: 3066113-06-9

Amount: USD 0.00

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Biological Activity

제품 설명

IC₅₀ & Target

^[1]

RDC Peptide

All Radionuclide-Drug Conjugates (RDCs) Isoforms :

In Vitro

RAYZ-8009 shows high binding affinity for mouse, canine, and cynomolgus monkey GPC3 proteins, and exhibits potent cell binding and efficient internalization in GPC3-positive HepG2 cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 3066113-06-9
분자량 1835.08
화학식 C₉₁H₁₁₉N₁₇O₂₂S
SMILES

CN(C([C@@H](NC([C@](NC([C@](NC([C@@H](NC([C@@H](N(C([C@@H](NC([C@](N(C([C@@H](N(C(CSC[C@H](N(C([C@@H](NC(CNC1=O)=O)CC2=CN=C(C3=CC=CC=C3)C=C2)=O)C)C(N)=O)=O)C)CCCCN)=O)C)([H])[C@@H](C)CC)=O)CC(O)=O)=O)C)CCC(N)=O)=O)CC4=CC=C(C=C4)C(O)=O)=O)([H])[C@@H](C)OC)=O)([H])[C@@H](C)CC)=O)CC5=CC=C(C=C5)OCC(O)=O)=O)[C@H]1CC6=CC7=C(C=CN=C7)C=C6
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Viering O, et al. Biodistribution and Radiation Dosimetry of [Ga]Ga-RAYZ-8009, a Glypican 3-Targeting Compound for Imaging of Hepatocellular Carcinoma. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2025 Nov 03;66(11):1737-1742.

[2]. Poot AJ, et al. [Ga]Ga-RAYZ-8009: A Glypican-3-Targeted Diagnostic Radiopharmaceutical for Hepatocellular Carcinoma Molecular Imaging-A First-in-Human Case Series. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2024 Oct 01;65(10):1597-1603.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References

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RAYZ-8009

All Radionuclide-Drug Conjugates (RDCs) Isoforms

Biological Activity

제품 설명

IC50 & Target

In Vitro

Chemical Information

순도&문서

References

Calculators

Help & FAQs

RAYZ-8009 Related Classifications

HY-P12340 Related Classifications

Bioz

Keywords

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