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Cat. No.: HY-181270

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RH01504

RH01504 is a HIF2α inhibitor with a K_d value of 5.42 nM against human HIF2α. RH01504 inhibits the growth of renal cancer cells. RH01504 can be used in research related to renal cell carcinoma.

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CAS No.: 301335-35-3
화학식: C₁₄H₁₂ClNO₃
분자량:277.70

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

RH01504 Chemical Structure

CAS No.: 301335-35-3

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

IC₅₀ & Target^[1]

HIF-2α

5.42 nM (Kd)

All HIF/HIF Prolyl-Hydroxylase Isoforms :

In Vitro

RH01504 (72 h) potently inhibits the proliferation of human 786-O renal cell carcinoma cells, with an IC₅₀ value of 1.35 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 301335-35-3
분자량 277.70
화학식 C₁₄H₁₂ClNO₃
SMILES

COC1=CC(C(C2=C(C=CC(Cl)=C2)N)=O)=CC=C1O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Zhou S, et al. Identification of novel HIF2α inhibitors: a structure-based virtual screening approach. J Enzyme Inhib Med Chem. 2026;41(1):2606435. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References

상품명:
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수량:
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RH01504

All HIF/HIF Prolyl-Hydroxylase Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

RH01504 Related Classifications

HY-181270 Related Classifications