Rhodomyrtone
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Rhodomyrtone is an antibiotic that can be found in the leaves of Rhodomyrtus tomentosa. Rhodomyrtone kills Gram-positive bacterial cells without causing bacteriolysis. Rhodomyrtone exhibits activity against a variety of Gram-positive bacteria, including Bacillus cereus, Bacillus subtilis, Enterococcus faecalis, Staphylococcus epidermidis, Streptococcus gordonii, Streptococcus pneumoniae, Streptococcus pyogenes and Streptococcus salivarius. Rhodomyrtone is applicable to studies related to bacterial infections.
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- Purity : 95%
- CAS No.: 468757-69-9
- 화학식: C26H34O6
- 분자량:442.54
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보관:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Biological Activity
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Chemical Information
- Protocol
- 순도&문서
- References
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Help & FAQs
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Biological Activity
제품 설명
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
11.4 μM
Compound: 5
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Growth inhibition of HEK293 cells
Growth inhibition of HEK293 cells
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[PMID: 28400231] |
In Vitro
Rhodomyrtone exhibits significant antimicrobial activity against Escherichia coli and Staphylococcus aureus[1].
Rhodomyrtone (24 h) potently inhibits the growth of various Gram-positive bacterial strains, including MRSA, with MIC values ranging from 0.19 to 1.56 μg/mL[2].
Rhodomyrtone (24 h) exhibits concentration-dependent bactericidal activity against Streptococcus pyogenes; the bactericidal rate reaches ≥99.9% when treated at 2MBC for 24 h, 4MBC for 6 h, and 8MBC for 5 h[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 468757-69-9
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Appearance Solid
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분자량 442.54
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화학식 C26H34O6
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Color White to off-white
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SMILES
CC(C)C[C@@H]1C2=C(O)C(C(CC(C)C)=O)=C(O)C=C2OC3=C1C(C(C)(C(C3(C)C)=O)C)=O
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Structure Classification
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Initial Source
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선적
Room temperature in continental US; may vary elsewhere.
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보관
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Protocol
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Gram Staining of Tissue Sections
Gram staining of tissue sections is a histochemical technique used to differentiate Gram-positive and Gram-negative bacteria within histological specimens based on differences in bacterial cell wall structure and dye retention, adapted from classical bacteriological Gram staining into tissue-compatible “histological Gram stain” variants. In tissue applications, modifications of the Brown-Hopps and Brown-Brenn methods are commonly used to improve differentiation of microorganisms embedded within host connective tissue and to reduce overstaining or loss of Gram-negative signal, which are known limitations of earlier approaches. The principle relies on crystal violet-iodine complex retention in Gram-positive organisms and subsequent decolorization and counterstaining steps that allow contrast visualization of Gram-negative organisms against tissue background.
순도&문서
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Data Sheet (270 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Rhodomyrtone Related Classifications
HY-N13668 Related Classifications
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