RS-25344
RS-25344 is a selective inhibitor of phosphodiesterase type IV (PDE4). RS-25344 increases intracellular cAMP (cyclic adenosine phosphate) concentration by inhibiting PDE4 activity. RS-25344 can be used in the study of inflammation, immune diseases, neurodegenerative diseases and cardiovascular diseases.
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- CAS No.: 152814-89-6
- 화학식: C19H13N5O4
- 분자량:375.34
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Sf9 | IC50 |
19 nM
Compound: 27; CHEMBL1232082
|
Inhibition of recombinant human PDE4D7 catalytic domain expressed in baculovirus infected sf9 cells using cAMP as substrate
Inhibition of recombinant human PDE4D7 catalytic domain expressed in baculovirus infected sf9 cells using cAMP as substrate
|
[PMID: 26908025] |
Chemical Information
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CAS No. 152814-89-6
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분자량 375.34
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화학식 C19H13N5O4
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SMILES
O=C1N(C2=CC=CC([N+]([O-])=O)=C2)C3=NC=CC=C3C(N1CC4=CC=NC=C4)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)