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Cat. No.: HY-156958

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S-72

S-72 inhibits tubulin polymerization and further triggers mitosis-phase cell cycle arrest and cell apoptosis, in addition to suppressing STAT3 signaling.

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CAS No.: 2446799-14-8
화학식: C₂₀H₂₂N₄O₃S
분자량:398.48

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

S-72 Chemical Structure

CAS No.: 2446799-14-8

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

S-72 inhibits tubulin polymerization and further triggers mitosis-phase cell cycle arrest and cell apoptosis, in addition to suppressing STAT3 signaling^[1].

All STAT Isoforms :

Chemical Information

CAS No. 2446799-14-8
분자량 398.48
화학식 C₂₀H₂₂N₄O₃S
SMILES

O=C(C1=CC=C(C)C(NS(=O)(C2=CC=C(C)C=C2)=O)=C1)NCC3=CN(C)N=C3
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Zhenyan Hou, et al. S-72, a Novel Orally Available Tubulin Inhibitor, Overcomes Paclitaxel Resistance via Inactivation of the STING Pathway in Breast Cancer. Pharmaceuticals (Basel). 2023 May 15;16(5):749. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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S-72

PTUPB

(+)-Erinacin A

Isogarcinol

PDIC-NN

All STAT Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

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Bioz

S-72

PTUPB

(+)-Erinacin A

Isogarcinol

PDIC-NN

All STAT Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

S-72 Related Classifications

HY-156958 Related Classifications

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