country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-N19921

Copy Link Print Information

Schizotenuin A

Schizotenuin A is a Aβ and hIAPP fibrillation inhibitor with human-derived IC₅₀ values of 2.93 µM and 0.58 µM, respectively, and exhibits antioxidant activity. Schizotenuin A scavenges DPPH free radicals and inhibits lipid peroxidation in rat liver microsomes. Schizotenuin A can be used in research related to Alzheimer's disease and type 2 diabetes.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 144608-09-3
화학식: C₃₆H₂₈O₁₆
분자량:716.60

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Schizotenuin A Chemical Structure

CAS No.: 144608-09-3

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

In Vitro

Aβ/Tau/α-Synuclein AggregationFerroptosis

Aβ/Tau/α-Synuclein Aggregation

Schizotenuin A (1-100 μM; 24 h) potently inhibits Aβ42 fibrillization with an IC₅₀ of 2.93 μM in a dose-dependent manner^[1].
Schizotenuin A (100 μM; 24 h) significantly reduces and shortens Aβ42 fibrils as visualized by TEM^[1].

Ferroptosis

Schizotenuin A (compound 40) inhibits lipid peroxidation in rat liver microsomes with an IC₅₀ of 36.25 μM, which is more potent than (+)-α-Tocopherol (HY-N0683)^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Chemical Information

CAS No. 144608-09-3
분자량 716.60
화학식 C₃₆H₂₈O₁₆
SMILES

OC(C=C1C[C@H](C(O)=O)OC(C(C2=CC(/C=C/C(O[C@@H](C(O)=O)CC3=CC(O)=C(C=C3)O)=O)=C4)=C(C5=CC(O)=C(C=C5)O)OC2=C4O)=O)=C(C=C1)O
Structure Classification
- Phenols
- Polyphenols
Initial Source
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Sun J, et al. Inhibitory activities of phenylpropanoids from Lycopus lucidus on amyloid aggregation related to Alzheimer's disease and type 2 diabetes. Journal of natural medicines. 2020 Jun;74(3):579-583. [Content Brief]

[2]. Chand K, et al. A review on antioxidant potential of bioactive heterocycle benzofuran: Natural and synthetic derivatives. Pharmacological reports : PR. 2017 Apr;69(2):281-295. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

견적 받기 해외재고보유

Other size

견적 받기