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Cat. No.: HY-188057

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Sirusertib

Name: Sirusertib
Brand: MedChemExpress
SKU: HY-188057
Price: 530.00 USD
Availability: InStock
Rating: 5 (1 reviews)

Sirusertib (WEE1A&Myt1-IN-1) is a dual Wee1A/Myt1 inhibitor, with an IC₅₀ of ≤10 nM against Wee1A and ≤20 nM against Myt1. Sirusertib is applicable for cancer-related research.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 3066062-53-8
화학식: C₂₇H₂₉N₉O₂
분자량:511.58

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Sirusertib Chemical Structure

CAS No.: 3066062-53-8

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

Sirusertib (WEE1A&Myt1-IN-1) is a dual Wee1A/Myt1 inhibitor, with an IC₅₀ of ≤10 nM against Wee1A and ≤20 nM against Myt1. Sirusertib is applicable for cancer-related research^[1].

All Wee1 Isoforms :

PKMYT1

In Vitro

Sirusertib (Compound 109) inhibits Wee1A and Myt1 with IC₅₀ values of ≤10 nM and ≤20 nM, respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 3066062-53-8
분자량 511.58
화학식 C₂₇H₂₉N₉O₂
SMILES

O=C1C2=CN=C(NC3=CC(C=NN4C)=C4C=C3)N=C2N(N1CC=C)C5=NC(OC6CCN(CC6)C)=CC=C5
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Hans Mattias JÖNSSON, et al. Pyrazolo-pyrimidinone compounds for use in methods of inhibiting wee1 a kinase. WO2024254490A1. WIPO (PCT). 2024-06-07.

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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