Sirusertib
Sirusertib (WEE1A&Myt1-IN-1) is a dual Wee1A/Myt1 inhibitor, with an IC50 of ≤10 nM against Wee1A and ≤20 nM against Myt1. Sirusertib is applicable for cancer-related research.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 3066062-53-8
- 화학식: C27H29N9O2
- 분자량:511.58
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocol
- 순도&문서
- References
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Help & FAQs
Biological Activity
제품 설명
In Vitro
Sirusertib (Compound 109) inhibits Wee1A and Myt1 with IC50 values of ≤10 nM and ≤20 nM, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 3066062-53-8
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분자량 511.58
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화학식 C27H29N9O2
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SMILES
O=C1C2=CN=C(NC3=CC(C=NN4C)=C4C=C3)N=C2N(N1CC=C)C5=NC(OC6CCN(CC6)C)=CC=C5
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocol
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Sirusertib Related Classifications
HY-188057 Related Classifications
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