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Cat. No.: HY-161864

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STAT3-IN-29

STAT3-IN-29 (Compound B20) is an inhibitor for STAT3. STAT3-IN-29 inhibits the proliferation of HaCaT cell with IC₅₀ of 0.09 µM, ameliorates the IMQ-induced psoriasis in mouse models.

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CAS No.: 2256751-16-1
화학식: C₂₀H₁₅NO₆
분자량:365.34

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

STAT3-IN-29 Chemical Structure

CAS No.: 2256751-16-1

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

STAT3-IN-29 (Compound B20) is an inhibitor for STAT3. STAT3-IN-29 inhibits the proliferation of HaCaT cell with IC₅₀ of 0.09 µM, ameliorates the IMQ-induced psoriasis in mouse models^[1].

IC₅₀ & Target

STAT3

All STAT Isoforms :

Chemical Information

CAS No. 2256751-16-1
분자량 365.34
화학식 C₂₀H₁₅NO₆
SMILES

COC(C=C1)=C(OC)C=C1CC2=NOC3=C2C(C4=C(O)C=CC=C4C3=O)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Chen L, et al. Synthesis and biological evaluation of novel isoxazoloquinone derivatives as potent STAT3-targeting antipsoriasis agents[J]. Bioorganic Chemistry, 2024: 107617.

Calculators

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Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

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Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References

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STAT3-IN-29

All STAT Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

STAT3-IN-29 Related Classifications

HY-161864 Related Classifications