country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-187907

Copy Link Print Information

Surbinsertib

Name: Surbinsertib
Brand: MedChemExpress
SKU: HY-187907
Availability: PreOrder

(Synonyms: SGR-3515)

Surbinsertib (SGR-3515) is an orally active dual inhibitor of the Wee1 and Myt1 kinases. Surbinsertib is used in cancer research.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 3038330-83-2
화학식: C₃₀H₄₀N₈O₂S
분자량:576.76

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Surbinsertib Chemical Structure

CAS No.: 3038330-83-2

사이즈

가격

재고

수량

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

Surbinsertib (SGR-3515) is an orally active dual inhibitor of the Wee1 and Myt1 kinases. Surbinsertib is used in cancer research^[1]^[2].

All Wee1 Isoforms :

PKMYT1

In Vitro

Both Wee1 and Myt1 are CDK-inhibitory kinases. Wee1 primarily phosphorylates CDK1‑Tyr15, while Myt1 phosphorylates both CDK1‑Tyr15 and Thr14. The two kinases act synergistically to inhibit CDK1 activity and regulate the G2/M cell cycle transition.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 3038330-83-2
분자량 576.76
화학식 C₃₀H₄₀N₈O₂S
SMILES

C[C@]12[C@](CC(C)(OC2)C)([H])N(C3=CC=CC(N=S(C)(C)=O)=N3)C4=NC(NC5=CC=C(N6CCN(CC6)C)C=C5)=NC=C41
Synonyms

SGR-3515
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. WHO Drug Information, Vol. 40, No. 2, 2026

[2]. Shaoxian Sun, et al, Abstract 3025: Optimization of therapeutic index of SGR-3515, a first-in-class Wee1/Myt1 inhibitor through intermittent dosing for monotherapy and combination with chemotherapy in xenograft tumor models. Cancer Res 15 April 2025; 85.

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

견적 받기 해외재고보유

Other size

견적 받기