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Cat. No.: HY-P11606

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WNT3Ap

WNT3Ap is a polypeptide corresponding to the hairpin 2 domain of the WNT3A protein. WNT3Ap undergoes palmitoylation modification catalyzed by PORCN. WNT3Ap is a key compound for elucidating the molecular mechanism of the Wnt signaling pathway and for developing PORCN inhibitors.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

화학식: C₁₀₈H₁₆₄N₃₂O₂₈S₅
분자량:2518.98

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

WNT3Ap Chemical Structure

사이즈

가격

재고

수량

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

All Wnt Isoforms :

In Vitro

WNT3Ap (50 μM; 37°C for 30 minutes) undergoes acylation by PORCN in vitro, with a Km value of 14.29 μM for palmitoyl-CoA^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

분자량 2518.98
화학식 C₁₀₈H₁₆₄N₃₂O₂₈S₅
Sequence

Met-His-Leu-Lys-Cys-Lys-Cys-His-Gly-Leu-Ser-Gly-Ser-Cys-Glu-Val-Lys-Thr-Cys-Trp-Trp-Ser-NH2 (Disulfide bridge:Cys5-Cys19,Cys7-Cys14)
Sequence Shortening

MHLKCKCHGLSGSCEVKTCWWS-NH2 (Disulfide bridge:Cys5-Cys19,Cys7-Cys14)
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (258 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Liu Y, et al. Mechanisms and inhibition of Porcupine-mediated Wnt acylation. Nature. 2022;607(7920):816-822. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References

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수량:
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WNT3Ap

All Wnt Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

WNT3Ap Related Classifications

HY-P11606 Related Classifications