XH-30
XH-30 is a potent, selective, and orally active PKMYT1 inhibitor, with an IC50 of 4.1 nM. XH-30 suppresses the proliferation of P53-mutated triple-negative breast cancer (TNBC) cells by inducing G2/M phase release, DNA damage, and apoptosis. XH-30 demonstrates antitumor effects in an MDA-MB-231 mouse model. XH-30 can be used for P53-mutated TNBC research.
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- CAS No.: 3077136-87-6
- 화학식: C19H19N3O3
- 분자량:337.37
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
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Help & FAQs
Biological Activity
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PKMYT1 4.1 nM (IC50) |
Chemical Information
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CAS No. 3077136-87-6
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분자량 337.37
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화학식 C19H19N3O3
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SMILES
NC1=C(C=C2N=C(OC2=C1C3=C(C(O)=CC=C3C)C)C4CC4)C(N)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
XH-30 Related Classifications
HY-180893 Related Classifications
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