YTHDF2 ligand-1
Based on 1 Customer Validation
YTHDF2 ligand-1 (Compound 23) is a competitive, selective, and high-affinity YTHDF2 ligand with an IC50 of 11 μM and a Kd of 1.3 μM. YTHDF2 ligand-1 competes with m6A-RNA for binding to YTHDF2. YTHDF2 ligand-1 is applicable for cancer research.
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- Purity : 98.83%
- CAS No.: 3093182-34-1
- 화학식: C14H12N4O2S2
- 분자량:332.40
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보관:
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
제품 설명
IC50 & Target
[1]|
YTHDF2 11 μM (IC50) |
YTHDF2 1.3 μM (Kd) |
In Vitro
YTHDF2 ligand-1 binds strongly to YTHDF2 with an IC50 of 11 μM, and exhibits high selectivity for YTHDF1 and YTHDF3[1].
YTHDF2 ligand-1 (1 h) binds to YTHDF2 with a Kd value of 1.3 μM and exhibits high selectivity, showing approximately 100-fold lower affinity for YTHDC1 and approximately 350-fold lower affinity for YTHDC2[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3093182-34-1
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Appearance Solid
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분자량 332.40
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화학식 C14H12N4O2S2
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Color White to off-white
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SMILES
CC1=C(SC2=C1C(NC(N2)=S)=O)C(NCC3=CN=CC=C3)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
순도&문서
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Data Sheet (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
YTHDF2 ligand-1 Related Classifications
HY-174982 Related Classifications
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