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Cat. No.: HY-122180

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ZINC08790006

ZINC08790006 is a high-affinity SIRT1 inhibitor, and it can be used in the research of SIRT1-related diseases (such as aging, diabetes and cancer).

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 2072170-41-1
화학식: C₁₇H₁₈N₄O₃
분자량:326.35

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (294 KB)

ZINC08790006 Chemical Structure

CAS No.: 2072170-41-1

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

ZINC08790006 is a high-affinity SIRT1 inhibitor, and it can be used in the research of SIRT1-related diseases (such as aging, diabetes and cancer)^[1]^[2].

IC₅₀ & Target

^[1]

SIRT1

All Sirtuin Isoforms :

In Vitro

ZINC08790006 exhibits high affinity for the catalytic domain of SIRT1 (PDB ID: 4I5I), with an estimated binding energy of −7.3 kcal/mol, which is consistent with the structural characteristics of potent SIRT1 inhibitors^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Research Protocol for Metabolic Diseases

Chemical Information

CAS No. 2072170-41-1
분자량 326.35
화학식 C₁₇H₁₈N₄O₃
SMILES

O=C1N(C)C(C(C2N(C)CCC3=C2NC4=C3C=CC=C4)=C(O)N1)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (294 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Sun Y, et al. Ligand-based virtual screening and inductive learning for identification of SIRT1 inhibitors in natural products. Scientific reports. 2016 Jan 25;6:19312. [Content Brief]

[2]. Alrouji M, et al. Targeting Sirtuin 1 for therapeutic potential: Drug repurposing approach integrating docking and molecular dynamics simulations. PloS one. 2023;18(12):e0293185. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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Other size

견적 받기

Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

상품명:
CAS No.:
Species:
Purity:
수량:

ZINC08790006

All Sirtuin Isoforms

Biological Activity

제품 설명

IC50 & Target

In Vitro

Chemical Information

순도&문서

References

Calculators

Help & FAQs

ZINC08790006 Related Classifications

HY-122180 Related Classifications

Bioz

Keywords

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