KRAS ligand 4
KRAS ligand 4 (compound 2) is a bifunctional molecular glue degrader based on SOS1. KRAS ligand 4 reduces downstream signaling markers pERK and pS6 and displays anti-additional activity in cells with multiple KRAS mutations.
For research use only. We do not sell to patients.
- Formula: C24H28ClF3N6O3
- Molecular Weight:540.97
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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Molecular Weight 540.97
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Formula C24H28ClF3N6O3
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SMILES
FC(F)(F)C1=CC([C@@H](C)NC2=NC(Cl)=NC3=C2CN(C(C4(OC)CCN(C(C)=O)CC4)=O)C3)=CC(N)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)