1. Metabolic Enzyme/Protease
  2. Tyrosinase
  3. Kurarinol

Kurarinol 

Cat. No.: HY-122933
Handling Instructions

Kurarinol is a flavanone found in the root of Sophora flavescens. Kurarinol is a competitive tyrosinase inhibitor, with IC50 of 0.1 μM for mushroom tyrosinase.

For research use only. We do not sell to patients.

Kurarinol Chemical Structure

Kurarinol Chemical Structure

CAS No. : 855746-98-4

Size Stock
100 mg   Get quote  
250 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Kurarinol is a flavanone found in the root of Sophora flavescens. Kurarinol is a competitive tyrosinase inhibitor, with IC50 of 0.1 μM for mushroom tyrosinase[1].

IC50 & Target

IC50: 0.1 μM (mushroom tyrosinase)[1]

In Vitro

Kurarinol manifests relatively low cytotoxic activity (EC50>30 μM)[1].
Kurarinol inhibits production of melanin in S. bikiniensis without affecting the growth of microorganism[1].
Kurarinol induces hepatocellular carcinoma cell apoptosis through suppressing cellular signal transducer and activator of transcription 3 signaling (STAT3)[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Kurarinol (20 mg/kg; p.o.; daily; for 3 days) reduced serum lipid levels in high-Cholesterol diet induced hyperlipidemic rats[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Sprague-Dawley rats (120-130g), hypercholesterolemic models[3]
Dosage: 20 mg/kg
Administration: Oral administration, daily, for 3 days
Result: Decreased serum TC, TG, and LDL-C levels.
Molecular Weight

456.53

Formula

C₂₆H₃₂O₇

CAS No.

855746-98-4

SMILES

CC([[email protected]](CCC(C)(O)C)CC(C(O)=C1)=C(O[[email protected]](C(C=CC(O)=C2)=C2O)CC3=O)C3=C1OC)=C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

KurarinolTyrosinasetyrosinasemushroomL-tyrosinasemapoptosisanti-cancerhypercholesterolemicatherosclerosisInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email address *

Phone number *

 

Organization name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Kurarinol
Cat. No.:
HY-122933
Quantity:
MCE Japan Authorized Agent: