Lactodifucotetraose
Based on 1 Customer Validation
Lactodifucotetraose is a difucosylated human milk oligosaccharide. Lactodifucotetraose inhibits platelet function and the release of inflammatory factors. Lactodifucotetraose can be used for the research of *Campylobacter jejuni*-associated diarrhea and platelet-induced inflammatory processes.
For research use only. We do not sell to patients.
- Purity: 99.80%
- CAS No.: 20768-11-0
- Formula: C24H42O19
- Molecular Weight:634.58
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
Lactodifucotetraose (0-10 mg/mL; 15 min pre-incubation; 2 h thrombin activation) dose-dependently inhibits thrombin-induced release of the proinflammatory proteins RANTES and sCD40L from isolated adult platelets[2].
Lactodifucotetraose (0-2 mg/mL; 15 min pre-incubation; 2 h incubation on collagen-coated wells) inhibits the adhesion of isolated adult platelets to collagen-coated surfaces in a dose-dependent manner[2].
Lactodifucotetraose (0-5 mg/mL; 5 min pre-incubation followed by agonist activation) dose-dependently inhibits aggregation and ATP release of isolated adult platelets activated by Collagen (HY-NP003) or ADP (HY-W010918)[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 20768-11-0
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Appearance Solid
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Molecular Weight 634.58
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Formula C24H42O19
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Color White to off-white
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SMILES
O[C@@H]([C@@H]([C@@H]([C@@H](O1)C)O)O)[C@@H]1O[C@H]([C@@H](O)C=O)[C@@H]([C@H](O)CO)O[C@H]2[C@@H]([C@H]([C@H]([C@H](O2)CO)O)O)O[C@H]3[C@H]([C@@H]([C@@H]([C@@H](O3)C)O)O)O
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Synonyms
Difucosyllactose ; 2′,3-Difucosyllactose
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Structure Classification
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Initial Source
human milk
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (274 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Zhang A, et al. Microbial production of human milk oligosaccharide lactodifucotetraose. Metab Eng. 2021;66:12-20. [Content Brief]
[2]. Newburg DS, et al. Lactodifucotetraose, a human milk oligosaccharide, attenuates platelet function and inflammatory cytokine release. J Thromb Thrombolysis. 2016;42(1):46-55. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Lactodifucotetraose Related Classifications
HY-N10530 Related Classifications
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