1. Autophagy
  2. Autophagy
  3. LC3-mHTT-IN-1

LC3-mHTT-IN-1 

Cat. No.: HY-130258
Handling Instructions

LC3-mHTT-IN-1 (Compound AN1) is a mHTT-LC3 linker compound, which interacts with both mutant huntingtin protein (mHTT) and LC3B but not with wtHTT or irrelevant control proteins. LC3-mHTT-IN-1 reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons.

For research use only. We do not sell to patients.

LC3-mHTT-IN-1 Chemical Structure

LC3-mHTT-IN-1 Chemical Structure

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Description

LC3-mHTT-IN-1 (Compound AN1) is a mHTT-LC3 linker compound, which interacts with both mutant huntingtin protein (mHTT) and LC3B but not with wtHTT or irrelevant control proteins. LC3-mHTT-IN-1 reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons[1].

Molecular Weight

411.04

Formula

C₁₅H₉Br₂NO₃

SMILES

BrC1=CC=C(C/2=C1)NC(C2=C/C3=CC(Br)=C(C(O)=C3)O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

LC3-mHTT-IN-1AutophagyInhibitorinhibitorinhibit

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LC3-mHTT-IN-1
Cat. No.:
HY-130258
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