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Cat. No.: HY-106305A

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Ledoxantrone trihydrochloride

(Synonyms: CI 958 trihydrochloride)

Ledoxantrone (CI 958) trihydrochloride is a DNA helicases inhibitor with an IC₅₀ of 0.17 μM. Ledoxantrone trihydrochloride can be used in the study of prostate cancer.

For research use only. We do not sell to patients.

CAS No.: 119221-49-7
Formula: C₂₁H₃₀Cl₃N₅OS
Molecular Weight:506.92

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Ledoxantrone trihydrochloride Chemical Structure

CAS No.: 119221-49-7

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

Ledoxantrone (CI 958) trihydrochloride is a DNA helicases inhibitor with an IC₅₀ of 0.17 μM. Ledoxantrone trihydrochloride can be used in the study of prostate cancer^[1].

IC₅₀ & Target

Helicase

All DNA/RNA Synthesis Isoforms :

Chemical Information

CAS No. 119221-49-7
Molecular Weight 506.92
Formula C₂₁H₃₀Cl₃N₅OS
SMILES

OC1=CC(SC2=C(NCCN)C=CC3=C2C4=NN3CCN(CC)CC)=C4C=C1.Cl.Cl.Cl
Synonyms

CI 958 trihydrochloride
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Lun L, et al. Antihelicase action of CI-958, a new drug for prostate cancer. Cancer Chemother Pharmacol. 1998;42(6):447-53. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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Ledoxantrone trihydrochloride

All DNA/RNA Synthesis Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Ledoxantrone trihydrochloride Related Classifications

HY-106305A Related Classifications